Hi Teck5,
Do post some photos of your system so we can have clearer understanding as to how things are set-up. Gathering from what you have conveyed, my guess a solution to the integration problem you are currently facing is to either go for a good 2-way monitors OR try find longer listening distance (in the case of multi drivers 3 or 4-way).
In a friend's set-up room size similar to yours (ar,15'W x 22'L x 9'H), his Mini2 driven by all Soulution gears (710 stereo amp, 720 pre, and 740 cdp) had all the desirable qualities you are looking for, PLUS when cranked up, able to drive his room like crazy with unbelievable wall shaking bass! Organ-sustained, acoustic-plucked, even reggae-punchy bass lines were handled with aplomb.. Believe me, the Mini2 can simply rock placed in a room that size!
But then again, I don't really know how much of that 'side opening' you mentioned is giving up on bass drive ability in your particular room without having any visual cues.

